Arc ELISA Kit for Rat(Rattus norvegicus) | EIAab.comArc ELISA Kit for Rat(Rattus norvegicus)

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Arc (Gene name),

Activity-regulated cytoskeleton-associated protein (Protein name ), ARC_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Arc;

Protein name:

Activity-regulated cytoskeleton-associated protein;

Alternative:

Activity-regulated gene 3.1 protein(Arg3.1);ARC/ARG3.1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2.

Function:

Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.

Subcellular Location:

Cytoplasm cytoskeleton Endosome Cytoplasmic vesicle secretory vesicle acrosome Cytoplasm cell cortex Cell projection dendrite Cell projection dendritic spine Cell junction synapse postsynaptic cell membrane postsynaptic density Cell junction synapse Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail.

Protein Attributes:

Sequence length:

396

Sequence:

50:

100:

150:

200:

250:

300:

350:

396:

RGMEVQDGLE | QAAEPSVTPL | PTEDETEALT | PALTSESVAS | DRTQPE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.10086

String:

Q63053

KEGG:

rno:54323

Uniprot:

Q63053

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ELISA Kit for Rat Activity-regulated cytoskeleton-associated protein

Cat.:

E7736h

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96T

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ELISA Kit for Rat Activity-regulated cytoskeleton-associated protein

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ELISA Kit for Rat Activity-regulated cytoskeleton-associated protein

Cat.:

E7736m

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Packing:

96T

ELISA Kit for Rat Activity-regulated cytoskeleton-associated protein

Cat.:

E7736r

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96T

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CLIA Kit for Rat Activity-regulated cytoskeleton-associated protein

Cat.:

U7736r

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Packing:

96T

CLIA Kit for Rat Activity-regulated cytoskeleton-associated protein

MSDS:

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CLIA Kit for Rat Activity-regulated cytoskeleton-associated protein

Cat.:

U7736h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Rat Activity-regulated cytoskeleton-associated protein

Cat.:

U7736m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Activity-regulated cytoskeleton-associated protein

Cat.:

P7736Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Activity-regulated cytoskeleton-associated protein

Cat.:

P7736Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Activity-regulated cytoskeleton-associated protein

Monoclonal Antibody for Rat Activity-regulated cytoskeleton-associated protein

Protein for Rat Activity-regulated cytoskeleton-associated protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites."
Lyford G.L. , Yamagata K. , Kaufmann W.E. , Barnes C.A. , Sanders L.K. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Lanahan A.A. , Worley P.F.
Neuron14:433-445(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;INDUCTION
tissue: Hippocampus.
2.

"Somatodendritic expression of an immediate early gene is regulated by synaptic activity."
Link W. , Konietzko U. , Kauselmann G. , Krug M. , Schwanke B. , Frey U. , Kuhl D.
Proc. Natl. Acad. Sci. U.S.A.92:5734-5738(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION
strain: Sprague-Dawley.
tissue: Hippocampus.
3.

"Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking."
Chowdhury S. , Shepherd J.D. , Okuno H. , Lyford G. , Petralia R.S. , Plath N. , Kuhl D. , Huganir R.L. , Worley P.F.
Neuron52:445-459(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH DNM2; SH3GL1 AND SH3GL3
4.

"Increased expression of the immediate-early gene arc/arg3.1 reduces AMPA receptor-mediated synaptic transmission."
Rial Verde E.M. , Lee-Osbourne J. , Worley P.F. , Malinow R. , Cline H.T.
Neuron52:461-474(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
5.

"Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA Receptors."
Shepherd J.D. , Rumbaugh G. , Wu J. , Chowdhury S. , Plath N. , Kuhl D. , Huganir R.L. , Worley P.F.
Neuron52:475-484(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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